Accutane 20mg is a medication containing isotretinoin, a powerful retinoid used primarily for the treatment of severe nodular acne. Let’s delve into the details:

1. Purpose and Mechanism:
   • Accutane is derived from vitamin A and works by reducing the production of oil (sebum) by the sebaceous glands in the skin.
   • It accelerates skin cell turnover, helping to prevent clogged pores and inflammation associated with acne.
2. Indications:
   • Severe Nodular Acne: Accutane is specifically prescribed for severe, cystic, or nodular acne that has not responded to other treatments, including antibiotics.
   • It is not typically used for mild or moderate acne.
3. Dosage and Administration:
   • The recommended dosage range for Accutane is 0.5 to 1 mg/kg/day.
   • It is administered orally in two divided doses with food.
   • Treatment duration usually spans 15 to 20 weeks.
4. Precautions and Warnings:
   • Birth Defects: Accutane can cause severe birth defects if taken during pregnancy. It is crucial to avoid pregnancy while on this medication.
   • iPLEDGE Program: Accutane is available only through the iPLEDGE program, which ensures strict monitoring and compliance.
   • Contraception: Women of childbearing potential must use two forms of birth control while taking Accutane.
   • Avoid Vitamin A Supplements: Refrain from taking vitamin supplements containing vitamin A during Accutane treatment.
   • Blood Donation: Do not donate blood while on Accutane and for at least 30 days after discontinuation.
5. Side Effects:
   • Common side effects include dry skin, chapped lips, and mild joint pain.
   • Rare but serious side effects may involve depression, liver abnormalities, and inflammatory bowel disease.
6. Monitoring:
   • Regular follow-up visits with a healthcare provider are essential.
   • Blood tests monitor liver function, lipid levels, and other potential side effects.